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Short term constipation generally goes away within 48-72 hours without significant impact to long-term health.  In many cases, using a mild laxative or even a natural remedy such as prune juice is enough to stimulate a bowel movement and eliminate the problem.  Recurring or chronic constipation problems, however, are very serious health issues and really demand the immediate attention of a healthcare professional. In the end the best colon cleansing solutions are those that dissolve the accumulated feces and undigested food in the gastrointestinal tract while also replenishing intestinal flora which help keep the digestive system operating smoothly.